Tropifexor
- Catalog NO.:A903437
- CAS No. : 1383816-29-2
- Molecular Formula:C29H25F4N3O5S
- Molecular Weight: 603.59
Note*
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Bulk Inquiry
1. Please click the to confirm the discount and stock quantity.
2. Click“Bulk Inquiry”to ask for quotations of other quantity.
3. The price does not include shipping and bank charges.
Product Details
CAS Number | 1383816-29-2 | Appearance | White powder |
Catalog Number | A903437 | MDL Number | MFCD31693060 |
Molecular Formula | C29H25F4N3O5S | Molecular Weight | 603.59 |
Boiling Point | Melting Point | ||
Flash Point | Density | ||
Synonyms | rel-2-((1R,3r,5S)-3-((5-cyclopropyl-3-(2-(trifluoromethoxy)phenyl)isoxazol-4-yl)methoxy)-8-azabicyclo[3.2.1]octan-8-yl)-4-fluorobenzo[d]thiazole-6-carboxylic acid | ||
Storage Condition | Store in a tightly closed container,in a cool and dry place |
Safety
GHS Pictogram | |||
Signal Word | Warning | UN Number | |
Hazard Statements | H302-H315-H319-H335 | Class | |
Precautionary Statements | P261-P301+P312-P302+P352-P304+P340-P305+P351+P338 | Packing Group |
Description
Tropifexor, also known as LJN452, is a farnesoid X receptor agonist for the Treatment of Cholestatic Liver Diseases and Nonalcoholic Steatohepatitis (NASH). Potent in vivo activity was demonstrated in rodent PD models by measuring the induction of FXR target genes in various tissues. Tropifexor has advanced into phase 2 human clinical trials in patients with NASH and PBC. |